At the moment I'm farming act 2 inferno with a barbarian friend. I started out carrying him with this build and we got him enough resistance gear that he really helps out in the group.
Smoke screen isn't a 100% uptime but you don't need it if you know how to dodge what you can dodge.
Here is the build: http://us.battle.net/d3/en/calculator/demon-hunter#bPZXTV!Yca!YcZZZb
The build is pretty self explanatory and you can easily change out tactical advantage for anything you wish, it's just how I like to play.
I also try to stack as much crit/crit damage as I can with attack speed rings. This build helped me carry a barb through act 1/2 inferno and we now have it on farm with minimal deaths